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Search Results for " gnrh receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
TP1288 Fertirelin Others
Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist).
T1494 Alarelin Acetate Alarelin GNRH Receptor
Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors.
T27837 Linzagolix GNRH Receptor
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,...
T5520 Cetrorelix Acetate Cetrorelix GNRH Receptor
Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.
T3630 Relugolix RVT-601,TAK-385 GNRH Receptor
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi...
T11174 (R)-Elagolix NBI-56418 GNRH Receptor
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a do...
T4102 Goserelin acetate Fertilan,ICI-118630 acetate,Zoladex Apoptosis , GNRH Receptor
Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
T5031 Elagolix sodium NBI-56418 sodium GNRH Receptor
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).
T10217L Abarelix R3827,PPI 149 GNRH Receptor
Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment.
T5520L Cetrorelix diacetate NS-75A,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate GNRH Receptor
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) ...
T21308 Histrelin Supprelin LA,Histrelin Acetate Others
Histrelin (Supprelin LA) acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It is considered a GnRH agonist. Histrelin is used in the treatment of hormone-sensitive cancers of th...
T22025 AG 045572 P450 , GNRH Receptor
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is metabolized by CYP3A and inhibits testosterone.
TP2337 Ganirelix Acetate GNRH Receptor
Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist
TP1896L1 Kisspeptin 234 acetate(1145998-81-7 free base) GPR , Kisspeptin
Kisspeptin 234 acetate is a kisspeptin receptor antagonist. Kisspeptin 234 inhibits kisspeptin-10 stimulation of IP (IC50 = 7 nM) and release of GnRH.
T10475 BAY-784 Others
BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R).
T23412 T 98475 Others
gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally active
T37003 GnRH antagonist 2
GnRH antagonist 2 (formula I) is a potent GnRH receptor antagonist with valuable applications in endometriosis research[1].
TP1896 Kisspeptin 234
Kisspeptin 234 is a kisspeptin receptor antagonist. Kisspeptin 234 inhibits kisspeptin-10 stimulation of IP (IC50 = 7 nM) and release of GnRH.
T76350 [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH, a luteinizing hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor antagonist [1].
T69383 NBI-42902
NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm). Tritiated NBI-42902 binds with high affinity (K(d) = 0.19 nm) to a single class of binding sites and can be disp...
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